The development of the insulin pen market is unstoppable

2019-11-20 08:46 Source:unknow Writer: admin
 
Since we first entered the campus, we have been exposed to a variety of writing pens, including pencils, ballpoint pens, pens, etc. We believe that we are no stranger to these pens, and the insulin injection pens that are now widely used in medicine seem to be The two objects that are completely incompatible with each other have a very subtle connection and combination. This pen-type syringe with insulin solution has created a precedent for "injection pen" medical devices.
 
An insulin pen injector (referred to as an insulin pen) is usually composed of three parts, namely: a pen body, a needle, and a drug cartridge. The pen body consists of a detachable cap and a pen holder. The magazine is also called a refill, which stores the liquid medicine for insulin. When injecting insulin, a disposable needle is required for hygiene and safety. Compared to glass pen injectors, insulin pens are safer, more convenient, and have more precise controllable doses. Therefore, the product has been warmly welcomed by many diabetic patients as soon as it is on the market, and its sales volume has increased year by year.
 
Due to the various advantages of insulin pens, it has achieved considerable development in some countries. According to the latest report from foreign medical information media, about 80% of diabetics in Europe currently use insulin pens to control blood sugar. About 75% of diabetics in Japan use insulin pens. There are also many people with diabetes in China and India who often use insulin pens. However, in the United States, since the country has not included the insulin pen in the National Health Insurance reimbursement, the insulin pen use rate is only 3% among American diabetics. (Note: According to the US Department of Health, there are about 21 million diabetes in the country. people). As can be seen from the above statistics, the penetration rate of insulin pens in the United States is far less than that in Europe and Japan.
 
At present, there are at least a dozen brands of insulin pens on the international market. In general, they can be divided into two categories, namely, insulin pens and pre-filled insulin pens that can be used for multiple injections. The biggest difference between the two is that it can be used multiple times. The former is a reusable product and the latter is a one-time use product.
 
The rapid development of the insulin pen market has accelerated the creation and production of a new batch of insulin pens.
 
Swiss YpsomedAG Medical Devices recently announced that they have invented a new type of disposable injection pen. The pen is made of inexpensive polypropylene (PP) material and has a liquid that can be used once. The needle is a telescopic fine needle, and the patient's pain is small when injecting. Since it can only be used once, this inexpensive injection pen minimizes the occurrence of infections.
 
China Vansea Medical Devices Co., Ltd. recently developed a new type of pen-type syringe, which can separate the powdered drug from the water for injection, greatly improving the shelf life, reducing the injection process, and the injection accuracy is higher, the patient only needs to put the pen At the end of the button, the insulin can be lyophilized into a liquid and injected into the skin. The product has a variety of uses, in addition to insulin injection, it is also suitable for injection of GLP-1, aspartame, ganin, liraglutide, and other peptide drugs and other bioengineered drugs.
 
Eli Lilly is also developing its own multi-purpose pen-type syringe. Medical experts believe that it will include osteoporosis treatments (such as salmon calcitonin), multiple sclerosis treatments (such as -2b interferon), and anemia. Therapeutic drugs (such as the eighth coagulation factor) and rheumatoid arthritis and other common diseases can be applied to the pen-type syringe for treatment at home, thereby reducing the pressure on the hospital outpatient service. Due to the use of the reusable inner storage bag, the patient can purchase a plurality of sachets (refills) at a time in a small refrigerator at home, and can inject drugs for himself at any time and avoid the trouble of hospital injection.
 
In fact, many bioengineered drugs are protein or peptide substances, and they can usually only be injected with lyophilized powder reconstituted solution. The introduction of low-cost disposable prefilled injection pens paved the way for the promotion of bioengineering new drugs. Because the prefilled disposable injection pens are processed in batches at the pharmaceutical factory, it is much easier to recover than the traditional glass ampoule lyophilized powder and the solution is used, and the outpatient workload in the hospital can be greatly reduced. In the future, patients with chronic diseases such as tumors, rheumatoid arthritis, anemia, osteoporosis, viral hepatitis, psoriasis, lupus erythematosus, etc., can use their own disposable prefilled injection pens at home. Since the prefilled disposable injection pen has accurately calculated the dosage in advance, it is very safe for the patient to self-inject at home. There is no risk of overdose of the drug. At the same time, the patient can also save the trouble of queuing and injecting the hospital.
 
In the future, with the rapid development and promotion of modern technology, it is believed that the international medical device industry will develop more injection pens that are convenient for patients. It is understood that since the introduction of insulin pens from Europe 10 years ago, the sales volume of insulin pens has increased year by year, and domestic insulin pens have also been developed. With the rapid increase in national income, it is believed that the various innovative injection pens developed abroad will have broad market prospects in China.

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